"Trichopol": side effects in women and men. Indications for the use of "Trichopolum"

- a fairly common infectious pathology, characterized by the course of inflammation in the bladder.

Is it possible to drink Trichopolum with cystitis?

Since the treatment of acute or chronic cystitis should be complex, an integral step is the intake of antimicrobial agents, the choice of which will come from the type of pathogen.

If a patient has trichomonas cystitis, then Trichopol is prescribed in combination with other drugs.

The tool itself does not belong to the group of antibiotics, but the mechanism of action is almost the same.

Instructions for use: dosages, treatment regimen

The main active component of Trichopolum is. The drug has several forms of release:

In most cases, for patients diagnosed with cystitis, the doctor prescribes Trichopolum in the form of tablets. Suppositories and suspension are suitable for patients with diseases of the kidneys and liver, as well as the gastrointestinal tract. The injection solution is applicable only in case of a complicated course of the disease.

Trichopol tablets can contain 250 mg or 500 mg of the main substance, so only the doctor sets the dosage, taking into account the general condition of the body, the weight of the patient, the severity of the pathology and the presence of symptoms. Based on this, the treatment regimen and duration is selected individually for each. If you rely on the instructions, then it says that the reception should be carried out 2-3 times a day, 1 tablet (250 mg). The course of admission is a week, in some cases - 10 days.

The ways of taking the medicine can also be different: drink the whole tablet with milk or water, or chew and swallow after eating. In advanced cases, doctors advise women to use vaginal suppositories with the metronidazole substance in parallel with taking Trichopolum. Basically, such a scheme is appropriate for diagnosing Trichomonas in the vaginal microflora.

Reception during pregnancy and lactation with cystitis

When Trichopol is prohibited for use in the 1st trimester. In subsequent trimesters, the doctor may prescribe the drug, if appropriate, but full medical supervision is necessary.

While feeding the baby breast milk taking the medicine is undesirable, since the main substance, metronidazole, penetrates into the mother's milk and adversely affects the child. If, nevertheless, Trichopol was prescribed, then for the duration of treatment it is necessary to stop breastfeeding the baby.

Reception by children with cystitis

Trichopol is prohibited for use in children under the age of 3 years. From 3 to 10 years, the dose is selected individually in the absence of contraindications. Starting from the age of 10, the drug is used in accordance with the dosages for adults.

Is it possible to drink for prevention

Since Trichopol is a drug, has a number of contraindications, as well as side effects, it should not be taken for prophylactic purposes. Its use is justified only if a person has a disease and there are no contraindications.

An exception is when a bacterial infection may recur. To prevent, the doctor prescribes a prophylactic course of 5 days after the main therapy after 30 days.

Adverse reactions

A therapeutic course using this medication can sometimes adversely affect the general condition of the body. Sometimes there are adverse reactions from different body systems, namely:

With such symptoms, you should contact your doctor as soon as possible, who will reduce the dosage or completely cancel the drug.

The opinion of patients and doctors

Trichopol has long been used in medical practice, so the opinion about this drug has already developed both among doctors and patients who took it. Previously, medical professionals prescribed it exclusively for venereal diseases, but today it is used in therapy different types infections.

Studying the reviews, it turned out that the opinion of patients diverges. Some say that the medicine gives a result for short time, while other patients did not see the expected effect. Doctors say that the medication may not work only in cases where the treatment regimen was incorrect or the pathogen was incorrectly installed.

Current view of doctors:

In my opinion, this is one of the many well-known antimicrobial drugs, indispensable in medical practice. Of course, there are downsides, like any other drug - side reactions, most often a feeling of nausea and bitterness in oral cavity.

Taras Maksimovich, doctor

I prescribe to patients with cystitis Trichopol together with other drugs regularly. I think it's quite effective. No complaints have yet been heard from patients.

Alina Alexandrovna, doctor

Hi all! I continue to talk about various drugs. I spoke about enterosgel “HERE”, about lavakol “HERE”, fortrans “THEHER”. Many have heard about this drug, but not everyone knows what this Trichopolum treats. Therefore, today we will analyze the question: is it possible to drink Trichopolum for prevention.

1. Is it possible to drink Trichopolum for prevention

I will answer immediately, "without water":

“As a measure of prevention, Trichopolum cannot be drunk!”

First of all, it is a medicinal substance that can treat various infections. It also perfectly deals with acne and has a depressing effect on almost all harmful microorganisms.

harmful bacteria

2. Useful information about Trichopolum

The use of this tool leads to the destruction of dangerous bacteria. Therefore, below we give an extensive list of diseases that he can cure.

The question arises: "How to take?" The attending physician, having studied your disease, will prescribe a drug, the dosage of which is individual for each person. It is usually prescribed in the form of tablets that are swallowed during a meal or after, washed down with water.

Its pharmacological action:

antibacterial, antimicrobial, antiprotozoal, antiulcer, trichomonacid, anti-alcohol (Trichopolum tablets cause an aversion to alcohol).

If you are afraid of the name of the drug, then its instructions will help you understand how wide the range of its application is.

3. Contraindications

This medicine should not be used:

with blood diseases, impaired movement control, liver failure, diseases nervous system,at pregnancy, during lactation

4. Reviews of the drug

Among the reviews, there were no unambiguous ones, as with reviews of other medicines. But mostly they are positive. For example, one woman took pills for 10 days for vaginosis, and also put candles. The treatment was so successful that she forgot about her illness.

The main condition prescribed in the instructions, without which a positive effect is not possible:

"During treatment, you can not drink alcohol, so as not to reduce the effect of tablets and suppositories."

Let's rest a bit and listen to a song about those who are treated with Trichopolum":

5. Indications for use

We have learned so much about this remedy that it is time to get acquainted with the indications:

trichomoniasis (acute, chronic); infections caused by protozoa; mixed bacterial infections (anaerobic and aerobic); gastric and duodenal ulcers; after surgery of the gynecological sphere, operations on the intestines, appendectomy; alcoholism (chronic).

6. Trichopol is good, but metronidazole is better

There are very cheap alternatives Russian production such as metronidazole. It is no worse than the above drug.

So what is better than Trichopolum? The answer is metronidazole. The mechanism of action, as well as the composition, side effects are almost the same, only metronidazole is much cheaper. There are other medicines that contain this medicine, such as

Flagyl, Klion, Efloran, Metrogil and others.

For the treatment of sexual diseases, for example, metronidazole suppositories are often prescribed, as well as in the treatment of many gynecological diseases.

“To understand which medicine will be more effective for you, only a doctor will help you figure it out.”

In parting, I want to say that as a preventive measure, Trichopolum should not be taken, because it is a medicine, moreover, which has many contraindications.

“And do not forget: any pill is poison!”

And now a video on a given topic: "Trichopolum: forms (candles and tablets), side effects, more gentle analogues"

Today I told you about the beneficial properties, contraindications and alternatives to the use of Trichopolum. Now the question is not for you: "Is it possible to drink Trichopolum for the prevention of diseases." To better understand medicines, subscribe to my blog, be the first to know about all the news in the field of treatment of ailments.

7. P.S. with Inspector Varnicke and the story "The operation ended successfully"

At the end of the article, according to tradition, we are engaged in the activation of cerebral circulation. Why are we meeting with my childhood friend Inspector Varnike.

Today we have a difficult task from the story:

"Operation completed successfully"

Please send your versions of answers in the form of comments to the article. The correct answer will be published next Monday 24 August 2016.

Reviews Trichopolum: detailed instructions by application

Instructions for use of the medicine Trichopolum (Metronidazole) in tablets and ampoules

When should Trichopolum (Metronidazole) be used?

diseases caused by protozoa (trichomoniasis, giardiasis, amoebiasis and amoebic liver abscess, bacterial vaginosis); anaerobic bacterial infections (peritonitis, abdominal and liver abscesses, inflammation of the uterus and its appendages, postoperative complications, diseases of the bronchi, lungs and pleura, meningitis, brain abscesses, skin infections, osteomyelitis, blood poisoning); conditions after surgery on the intestines, appendectomy, gynecological operations (for the prevention of complications); mixed infections caused by anaerobic and aerobic microorganisms - in combination with an antibiotic that affects aerobic microorganisms; peptic ulcer of the stomach and duodenum as part of complex therapy; chronic alcoholism.

Dosage of Trichopol (Metronidazole)

Trichopol is prescribed orally, during or after a meal, the tablets are taken without chewing.

Trichopol (Metronidazole) tablets

With Trichomoniasis

Adults and children over 10 years of age are prescribed 250 mg (1 tablet) 3 times a day or 500 mg (2 tablets) 2 times a day for 7 days. Children aged 3 to 7 years are prescribed 125 mg (1/2 tablet) 2 times a day; from 7 to 10 years - 125 mg (1/2 tablet) 3 times a day. The course of treatment is 7 days.

For bacterial vaginosis

Adults are prescribed 500 mg (2 tablets) 2 times a day for 7 days or 2000 mg (8 tablets) once. Simultaneous treatment of the sexual partner is not required.

With Amebiasis

In invasive forms of intestinal amoebiasis, adults and children over 10 years of age are prescribed 750 mg (3 tablets) 3 times a day. Children aged 3 to 7 years - 250 mg (1 tablet) 4 times a day; at the age of 7 to 10 years - 375 mg (1.5 tablets) 3 times a day. The course of treatment is usually 5 days. With amoebic liver abscess and other forms of extraintestinal amebiasis, adults and children over 10 years of age are prescribed 375 mg (1.5 tablets) 3 times a day. Children aged 3 to 7 years - 125 mg (1/2 tablet) 4 times a day; at the age of 7 to 10 years - 250 mg (1 tablet) 3 times a day. The course of treatment is 5 days.

With Giardiasis

Adults and children over 10 years of age are prescribed 500 mg (2 tablets) 2 times a day for 5-7 days; or 2000 mg (8 tablets) 1 time per day for 3 days. Children aged 3 to 7 years - 250-375 mg (1-1.5 tablets) 1 time per day for 5 days, or 500-750 mg (2-3 tablets) 1 time per day for 3 days. Children aged 7 to 10 years - 250 mg (1 tablet) 2 times a day for 5 days, or 1000 mg (4 tablets) 1 time per day for 3 days.

For infections caused by anaerobic bacteria

Adults - 400 mg 3 times a day for 7-10 days; children under 12 years old - 7.5 mg / kg 3 times a day.

With peptic ulcer of the stomach and duodenum

Assign 500 mg (2 tablets) 3 times a day for 7 days (as part of combination therapy).

Prevention of infections caused by anaerobic bacteria (before abdominal surgery, in gynecology and obstetrics)

Adults and children over 12 years of age are prescribed 250-500 mg (1-2 tablets) 3 times a day 3-4 days before surgery. 1-2 days after the operation, 250 mg (1 tablet) is prescribed 3 times a day for 7 days.

With chronic alcoholism

Inside, 500 mg (2 tablets) 1 time per day for 6 (no more) months.

Trichopol solution for intravenous administration

For infections caused by anaerobic bacteria, adults and children over 12 years of age are prescribed the drug intravenously every 8 hours, 100 ml of a 0.5% solution (500 mg). Infusion is carried out at a rate of 5 ml/min. The maximum daily dose for intravenous administration is 4 g. The course of infusion therapy is 7-10 days, if necessary, 2-3 weeks. For children under 12 years of age, the dose for intravenous administration is set at the rate of 7.5 mg / kg of body weight (1.5 ml of a 0.5% metronidazole solution) every 8 hours. The drug is administered intravenously by drip, slowly. For the prevention of infections caused by anaerobic bacteria (before surgical operations on the abdominal cavity, in gynecology and obstetrics) For adults and children over 12 years old, the drug is administered at a dose of 500 mg (100 ml of a 0.5% solution) in/in drip slowly, the infusion is repeated after 8 hours Prophylactically, the drug is used no more than 12 hours after surgery.

Trichopol vaginal tablets

For nonspecific vaginitis, 1 vaginal tablet is prescribed in combination with 2 tablets of Trichopolum for oral administration per day for 7 days or 1 vaginal tablet 2 times a day. The duration of treatment is no more than 10 days, courses of treatment should be carried out no more than 2-3 times a year. With trichomonas vaginitis, 1 vaginal tablet is prescribed per day for 10 days in combination with the intake of Trichopolum inside. The vaginal tablet should be removed from the contour pack, moistened with boiled chilled water and inserted deep into the vagina.

Side effects when using the drug Trichopolum (Metronidazole)

From the side digestive system: pain in the stomach, nausea, vomiting, diarrhea, constipation, intestinal colic, decreased or no appetite, taste disturbance, unpleasant metallic taste in the mouth, dry mouth, glossitis, stomatitis; very rarely - abnormal liver function tests (ALT, AST, Bilirubin), jaundice, pancreatitis. From the nervous system: with prolonged use - headache, dizziness, impaired coordination of movements, ataxia, peripheral neuropathy, irritability, irritability, depression, sleep disturbance, drowsiness, weakness; in some cases - confusion, hallucinations, convulsions; very rarely - encephalopathy. From the urinary system: cystitis, polyuria, urinary incontinence, staining of urine in red-brown color. From the reproductive system: excessive development of the fungal flora of the vagina (including vaginal candidiasis), pain in the vagina. Allergic reactions: skin rash, itching, urticaria, nasal congestion, fever. From the musculoskeletal system: myalgia, arthralgia. From the hemopoietic system: leukopenia; rarely - agranulocytosis, neutropenia, thrombocytopenia. Other: extremely rare - toxic effect on the hearing aid; pustular eruptions.

Contraindications to the use of the drug Trichopolum (Metronidazole)

Trichopol is categorically contraindicated in the following cases: hypersensitivity to metronidazole; blood diseases, leukopenia (including in the past); impaired coordination of movements, organic lesions of the nervous system (including epilepsy); severe hepatic and kidney failure; pregnancy (I trimester); lactation period.

Use of the drug Trichopol during pregnancy and lactation

Trichopol can not be taken in the first trimester of pregnancy. The use of the drug in the II and III trimesters is possible only in cases where the intended benefit to the mother outweighs the potential risk to the fetus. If necessary, the use of Trichopolum during lactation breast-feeding should stop for a while.

Special instructions for the use of the drug Trichopolum

Trichopol can cause serious side effects in patients with impaired liver, kidney, bone marrow, nervous system function, as well as in elderly patients. Violation of gait, dizziness and any other deterioration in the neurological status of patients requires discontinuation of treatment with Trichopolum. With prolonged therapy with metronidazole (more than 10 days), the picture of peripheral blood and liver function should be monitored. The possibility of developing dizziness should be taken into account when prescribing the drug to patients whose activities are related to the control of mechanisms, especially drivers of vehicles. Do not drink alcohol while taking Trichopolum.

Interaction of the drug Trichopolum with other drugs

The combined use of Trichopolum with some antibiotics (for example, erythromycin, gentamicin) enhances their antibacterial effect. At the same time, when taking certain sleeping pills (for example, phenobarbital), the effect of Trichopolum may decrease. Therefore, before you start using Trichopolum, tell your doctor about other medicines you are taking.

Expert opinion of Polismed medical board

We have collected frequently asked questions and prepared answers to them.

How to take Trichopol?

Is there a difference in the dose in the treatment with Trichopolum regarding the disease (with giardiasis and with thrush, for example)?

Answer of the Medical Board

First of all, it should be clear that with thrush Trichopolum is not the first-line drug of choice and is used extremely rarely. This means that it does not have an antifungal effect, and its appointment with this diagnosis is justified only in the case of a chronic form, when thrush is accompanied by secondary infections.

With giardiasis, Trichopolum is allowed to be prescribed to children from the age of 3 according to the scheme:

3 - 7 years - within 5 days once at a dose of 250-375 mg. 7 - 10 years - course of treatment - 5 days, 2 tablets (250 mg) per day. Children after 10 years and adults - 6 days, 500 mg every 12 hours.

Regarding how to take Trichopol tablets before or after meals, and how many times a day to drink them - the drug is taken after or during meals, washed down with water, do not chew, in a dose according to age and doctor's prescription. How many days to take - also depends on the primary diagnosis, for example, with alcoholism it is allowed to drink up to 6 months, with giardiasis - no longer than 7 days. Some sources also indicate that Trichopolum helps with acne (Trichopolum tablet should be crushed into powder, mixed with water and applied to the problem area of ​​the face).

Can Trichopolum be given to children?

How correctly, in what dose and from what age is Trichopolum allowed to be given to children?

Answer of the Medical Board

First, it is worthwhile to understand that children under one year old cannot be used. Its use is allowed only after 3 years of age. Usually Trichopolum is assigned to children from lamblia. Depending on the diagnosis, the dosage is 1-2 tablets 3-4 times a day.

In exceptional cases, it can be used in children under 3 years of age with diarrhea that lasts more than 10 days. A single dose in this case should be calculated as follows: 5 mg of Trichopolum per 1 kg of body weight of the child, taking a dose every 8 hours for 48 hours.

Can Trichopolum be taken by pregnant or lactating women?

Is it really forbidden to take Trichopol during pregnancy on early dates and while breastfeeding?

Answer of the Medical Board

During pregnancy, Trichopol is categorically contraindicated, especially in the first 12 weeks of pregnancy. It is allowed to prescribe it to pregnant women only if the benefit to the mother outweighs the risk to the fetus.

During lactation, its use is also contraindicated, since the drug passes into breast milk. For the duration of treatment, it is worth stopping breastfeeding, it can be resumed 2 days after the last tablet of Trichopolum.

How to take Trichopolum for a man?

How to drink Trichopolum correctly and in what dose for a man in case of diagnosed trichomoniasis?

Answer of the Medical Board

In the case of diseases that are sexually transmitted, it is important that both partners undergo treatment with Trichopolum at the same time, which also applies to trichomoniasis. A man should take 1 tab. per day for 10 days. A woman is prescribed the same course, but 2 tab. per day, and additionally for a vaginal suppository 1 time in 24 hours.

In what form is it better to take - tablets or suppositories?

Tell me, in what pharmacological form is Trichopolum more effective - in suppositories or tablets?

Answer of the Medical Board

The choice of the form of the drug depends on the indication on the basis of which Trichopol was prescribed. With trichomanod vaginitis, vaginal tablets are prescribed, which must be soaked in water before administration. If vaginitis is nonspecific or bacterial in nature, then suppositories are combined with oral administration of tablets. For peptic ulcers, it is taken before meals in the form of regular tablets. In case of giardiasis, amoebiasis, etc. treatment with tablets is supposed.

Trichopol price photo Trichopolum - price and general description of this antimicrobial agent. Among the wide variety of all kinds of drugs for acne, there is always one or two myths, but Trichopol tablets cannot be attributed to their number. Many residents believe that this remedy able to cope with infectious diseases, sexually transmitted diseases. And this, in fact, is true, however, besides this, Trichopolum also fights pathogens that inhabit the human body.

If the main course of antibacterial medicines did not bring results, and acne remained unchanged, and tests for the presence of demodicosis and the presence of gastrointestinal diseases showed negative results, it is Trichopolum that can help you. The effect of this drug can be achieved if acne and pustules appeared as a result of the activity of anaerobes. In addition, this remedy is extremely effective in the treatment of sexually transmitted diseases provoked by Trichomonas, for example, trichomoniasis.

Instruction Trichopolum includes the following recommendations: the course of treatment involves taking two tablets daily for ten days. Together with this drug, it is allowed to apply ointments or gels containing metronidazole to areas of skin damaged by ticks.

In accordance with the instructions for Trichopolum, the active ingredient of the drug is metronidazole. The excipients that make up the tablets are magnesium stearate, starch syrup, gelatin, potato starch.

Trichopol is a derivative of 5-nitroimidazole. The mechanism of action of the drug is due to the biochemical reduction of the 5-nitro group of metronidazole due to the transport proteins of anaerobic protozoa and microorganisms. The reduced 5-nitro group interacts with the DNA cells of microorganisms, blunting the synthesis of their nucleic acids, which also leads to their death.

When applied, Trichopolum is active against Clostridia, Fusobacteria, Bacteroids, Amoebas, Balantidia, Trichomonas and Giardia.

The drug does not have a bactericidal effect on most facultative anaerobes, bacteria, viruses and fungi. In the presence of mixed flora (anaerobes and aerobes), the drug shows synergy when combined with antibiotics that are active against normal aerobes.

When used, Trichopol enhances the sensitivity of tumors to radiation, promotes sensitization to ethanol, and also activates reparative processes.

When taken orally, the substance is rapidly absorbed from the gastrointestinal tract. Metronidazole has a high bioavailability. The maximum concentration in blood plasma reaches in 1-3 hours. Poorly binds to blood proteins. According to the instructions, Trichopol penetrates into seminal fluid, vaginal secretions, breast milk, abscess cavities, amniotic fluid, saliva, bile, brain, cerebrospinal fluid, skin, liver, kidneys and lungs. Metabolized in the liver. Excreted from the body through the kidneys. The period of complete elimination is from 12 to 24 hours.

Indications for Trichopolum are:

• Infections caused by microorganisms sensitive to it;
• Abscessing pneumonia;
• Severe form of hepatic and intestinal amoebiasis;
• brain abscesses;
• skin infections;
• Abscesses of the pelvic organs;
• Osteomyelitis;
• gynecological infections;
• Peritonitis;
• gas gangrene;
• Sepsis.

Trichopol is prescribed for the prevention and treatment of anaerobic infections during surgical operations, as well as in combination therapy for mixed aerobic-anaerobic infections.

For the purpose of prevention, it is taken in an initial dose of 1-1.5 g once, and then - 0.75 g per day, divided into 3 doses. For treatment, adults take 0.75-1.5 g per day, children from 6 to 12 years old - 0.375 g each, divided into 3 doses.

Trichopol tablets are taken orally during or after meals. Duration of treatment - no more than 7 days.

For more effective therapy, treatment of two partners is necessary.

Women are prescribed 1 tablet 2 times a day orally and 1 vaginal suppository 1 time per day for 10 days, men - 1 tablet orally 2 times a day.

Take 1 g per day for 2 doses (morning and evening). The duration of treatment is 7 days.

• Helicobacter pylori eradication:

Take 0.25 g 2 times a day. The duration of therapy is 1-2 weeks. For patients with hepatic insufficiency, the usual dosage is reduced by 30% to prevent accumulation of metronidazole and the development of hepatic coma.

Patients with renal insufficiency, as a rule, do not need dosage adjustment. In the case of hemodialysis, a second course of treatment with Trichopolum is carried out.

For elderly patients, the drug is prescribed in reduced dosages. Reception is carried out under close medical supervision.

In reviews of Trichopolum, it is reported that the drug can cause adverse reactions from the body:

• Gastrointestinal tract: dyspepsia. metallic taste and dry mouth, reversible drug-induced pancreatitis, stomatitis, hepatitis. change in the level of liver tests;
• Central nervous system and sensory organs: cerebellar syndrome, dizziness. ataxia. headaches, diplopia. myopia, neuropathy;
• Organs of hematopoiesis: agranulocytosis, thrombocytopenia, anemia. decrease in the number of blood cells;
• Other: discoloration of urine, allergic rash, angioedema, anaphylactic shock, rashes.

Even according to the indications, Trichopolum is not prescribed in such cases:

• Children's age up to 6 years;
• Leukopenia;
• Hypersensitivity to its components;
• 1 trimester of pregnancy;
• Liver failure;
• Organic lesions of the central nervous system;
• lactation period.

In the 2nd and 3rd trimester of pregnancy, it is possible to prescribe Trichopol according to indications and under the strict supervision of the attending physician.

In case of an overdose of Trichopolum, according to reviews, dizziness, nausea, and vomiting are observed. In severe cases, convulsions, paresthesias and ataxia are possible. Treatment is symptomatic.

According to the active substance, the analogues of Trichopolum are Bacimex, Klion, Metrogil, Siptrogil, Flagyl.

With the simultaneous use of Trichopol with warfarin, the effect of the second is enhanced.

Cimetidine inhibits the metabolism of the drug, thereby increasing its concentration in the blood plasma and increasing the risk of side effects.

When combined with drugs that stimulate the activity of microsomal liver enzymes, it is possible to accelerate the elimination of Trichopolum and reduce its concentration in the blood.

Do not combine the drug with non-depolarizing muscle relaxants.

Sulfonamides enhance the antimicrobial effect of Trichopolum.

With the simultaneous use of Trichopol with disulfiram, various neurological disorders may develop, so the interval between taking these drugs should be at least 2 weeks.

With prolonged treatment with the drug, it is necessary to regularly monitor the pattern of peripheral blood and liver function.

According to the instructions and reviews, Trichopol is incompatible with alcohol.

The drug can stimulate the immobilization of treponemas, resulting in a false positive result of the Nelson test.

During the period of therapy, activities that require an increased concentration of attention and speed of psychomotor reactions should be avoided.

The instructions for Trichopolum indicate that the tablets should be stored in a dark, dry, cool and out of the reach of children place.

From drugstores it is released under the prescription of the doctor.

Shelf life - 3 years.

The drug Trichopol finds application in many cases. Most often it is used in complex therapy. various diseases caused by protozoa. How to take Trichopolum correctly? What precautions should be taken? Can Trichopolum be taken during pregnancy? What side effects does Trichopolum have and does Trichopolum help get rid of acne? We will cover all this in this article.

Trichopol contains the main pharmacological substance metronidazole. It is the properties of this component that determine the degree of influence of the drug on the human body. Most often, Trichopol is used in cases where such a pharmacological effect is necessary, such as:

• impact on protozoan microorganisms;
• antibacterial effect on gram positive and gram negative bacteria.

Trichopolum also has the ability to increase the sensitivity of oncological tumors to gamma rays. This allows Trichopolum to find its application in radiation therapy of cancer patients.

A completely unique property of Trichopolum is the ability to cause disgust for alcohol. It has a sensitizing effect on alcohols. The patient ceases to feel dependence on alcohol.

Instructions for use of Trichopolum tablets and suppositories are written in rather dry medical language. Therefore, in many patients, Trichopolum is still associated with the treatment of trichomoniasis and other sexually transmitted diseases. In practice, this is absolutely not true. The fact is that Trichopol is used for various diseases, ranging from the sanitation of the oral cavity from bacteria that cause caries and ending with the treatment of duodenal ulcer.

However, during the period of application of Trichopolum, certain recommendations should be strictly observed. We will present some of them below. So, treatment with Trichopolum should be started only after consulting with your doctor.

• take Trichopolum for no longer than 10 days;
• during treatment, exclude any dose of alcohol;
• do not take trichopol in the first trimester of pregnancy;
• do not combine the use of Trichopolum and certain types of antibiotics at the same time, such as amoxicillin;
• Trichopolum should be taken after meals with a glass of big amount water or milk;
• when the first side effects appear, the drug Trichopolum should be stopped and consult a doctor.

It should also be remembered that children under 3 years of age should not be given Trichopol tablets in tablets. Alternatively, anal suppositories can be used.

To date, the price of Trichopolum fluctuates around fifty rubles for a standard package containing twenty tablets. This is acceptable enough for most of our fellow citizens. The course of treatment requires one package of the drug. Trichopolum, the price of which is below the mentioned level, is most likely produced in Russia. This does not reduce its therapeutic effect. But side effects due to a decrease in chemical purity may occur more often.

When we prescribe Trichopolum, patient feedback is critical. In some difficult cases of therapy acne and various diseases of the oral cavity, this plays an important role. After all, only the positive experience of another patient can most convincingly influence the patient.

Trichopolum indications for use are very different. Most often, this drug is used to treat:

• giardiasis;
• peptic ulcer of the stomach and duodenum;
• trichomoniasis;
• bacterial vaginosis;
• amoebiasis;
• caries and periodontitis;
• sepsis;
• myocarditis;
• endocarditis;
• many other serious infections, including in the treatment of acne.

The use of Trichopol should be started only after clear indications have been established. Depending on the type of disease, there are various treatment regimens. Be sure to consult your doctor before use. Trichopol tablets should be taken orally without chewing.

Trichopolum suppositories are used to treat bacterial vaginosis and trichomoniasis. Trichopolum tablets are used in all other cases. However, treatment with Trichopolum and genital infections is allowed in tablet form. What proportion of your particular case to choose is determined by the attending physician.

Treatment with Trichopolum should be carried out systematically. Like any other antibacterial drug, with irregular use, it quickly causes bacteria and protozoa to get used to it. In the future, treatment with Trichopolum will not make any sense. Moreover, Trichopol tablets in this case can cause even more rapid growth of microbes, serve as a nutrient medium for them.

Trichopolum and alcohol are not compatible concepts. Trichopol tablets cause persistent alcohol intolerance even in minimal amounts. Therefore, while taking Trichopolum, you should not drink alcohol. Also, after the course of treatment is over, alcohol should not be consumed within 48 hours.

During pregnancy, Trichopolum can be taken only in extreme cases. During the first trimester of pregnancy, it is contraindicated categorically.

During lactation and breastfeeding, the child is weaned and transferred to artificial feeding while taking Trichopolum.

Side effects of Trichopolum can be manifested in various forms. As a rule, it is observed:

• indigestion associated with liquid stool, increased gas formation and nausea;
• the blood picture may change;
• in some cases, there is a general inhibition of reactions, headaches, dizziness.

At the first symptoms that side effects of Trichopolum are manifested, it should be noted that the drug is taken.

With giardiasis and trichomaniasis, Trichopolum is usually prescribed 2 tablets 2 times a day. In all other cases, 1 tablet 3 times a day. But the exact dosage can be calculated only after a comprehensive examination and identification of combinations of various infections.

If you are taking Trichopolum for acne, then the course of treatment cannot be less than 5 days. In this case, Trichopol should be taken 1 tablet 3 times a day.

Sources:
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Treatment is carried out simultaneously for both sexual partners. Inside, during meals or after meals (or drinking milk), without chewing.

Orally 750 mg (3 tablets) 3 times a day for 5-10 days. Children: 35 - 50 mg/kg body weight per day, in 3 divided doses, for 10 days.

Children: 2 to 5 years: 250 mg/day. 6 to 10 years: 375 mg/day. Over 10 years and adults: 500 mg/day. The daily dose should be divided into 2 doses. The course of treatment is usually 5-10 days. If necessary, according to the decision of the doctor, the treatment can be repeated after 4-6 weeks.

Infections caused by anaerobic bacteria.

Metronidazole can be used alone or in combination with other antibacterial drugs. The average treatment period should not exceed 7 days.

Adults and children over 12 years old: 1 - 2 tablets of 250 mg 3 times a day during or after meals.
Newborns and children up to 12 years: 7.5 mg/kg body weight, 3 times a day during or after meals.

Prevention of infections caused by anaerobic bacteria (before abdominal surgery, in gynecology and obstetrics)

Adults and children over 12 years: first 1 g (4 x 250 mg tablets) as a single dose, then 1 tablet of 250 mg 3 times a day during or after meals.

Children from 5 to 12 years old: 125 mg every 8 hours for 2 days. Newborns and children under 5 years: 5 mg/kg of body weight every 8 hours for 2 days.

From the side:

Digestive system: intestinal colic, pancreatitis;
- nervous system: taxia, confusion, weakness, hallucinations;
- allergic reactions: nasal congestion, arthralgia;
- genitourinary system: cystitis, polyuria, urinary incontinence;
- others: neutropenia, flattening of the T wave on the ECG.

The effect of the drug Trichopolum on driving a car and performing work that requires a high rate of mental and physical reactions. There are no data on the topic of contraindications for driving vehicles and servicing mechanical equipment.

The lethal dose for humans is unknown. In case of poisoning, apply symptomatic and supportive treatment.

In combination with amoxicillin, it is not recommended to use the drug in patients under 18 years of age. With leukopenia, the possibility of continuing treatment depends on the risk of developing an infectious process. May immobilize trelonemas and lead to a false positive Nelson test.

In the treatment of trichomonas vaginitis in women and trichomonas urethritis in men, it is necessary to refrain from sexual activity. Mandatory simultaneous treatment of sexual partners. Treatment does not stop during menstruation.

After therapy for trichomoniasis, control tests should be carried out for three regular cycles before and after menstruation.

After treatment of giardiasis, if symptoms persist, perform 3 stool tests at intervals of several days after 3-4 weeks (in some successfully treated patients, lactose intolerance caused by invasion may persist for several weeks or months, resembling the symptoms of giardiasis).

Trichopolum. Interaction with other drugs.

Trichopolum. Best before date.

5 years. Do not use the drug after the expiration date.

Trichopolum. Holiday conditions.

On prescription.

Instructions for use of the medicine Trichopolum (Metronidazole) in tablets and ampoules

When should Trichopolum (Metronidazole) be used?

Dosage of Trichopol (Metronidazole)

Side effects when using the drug Trichopolum (Metronidazole)

Contraindications to the use of the drug Trichopolum (Metronidazole)

Use of the drug Trichopol during pregnancy and lactation

Special instructions for the use of the drug Trichopolum

Interaction of the drug Trichopolum with other drugs

Expert opinion of Polismed medical board

Reviews Trichopolum: detailed instructions for use

diseases caused by protozoa (trichomoniasis, giardiasis, amoebiasis and amoebic liver abscess, bacterial vaginosis); anaerobic bacterial infections (peritonitis, abscesses of the abdominal cavity and liver, inflammation of the uterus and its appendages, postoperative complications, diseases of the bronchi, lungs and pleura, meningitis, brain abscesses, skin infections, osteomyelitis, blood poisoning); conditions after surgery on the intestines, appendectomy, gynecological operations (for the prevention of complications); mixed infections caused by anaerobic and aerobic microorganisms - in combination with an antibiotic that affects aerobic microorganisms; peptic ulcer of the stomach and duodenum as part of complex therapy; chronic alcoholism.

Trichopol is prescribed orally, during or after a meal, the tablets are taken without chewing.

With Trichomoniasis

Adults and children over 10 years of age are prescribed 250 mg (1 tablet) 3 times a day or 500 mg (2 tablets) 2 times a day for 7 days. Children aged 3 to 7 years are prescribed 125 mg (1/2 tablet) 2 times a day; from 7 to 10 years - 125 mg (1/2 tablet) 3 times a day. The course of treatment is 7 days.

For bacterial vaginosis

Adults are prescribed 500 mg (2 tablets) 2 times a day for 7 days or 2000 mg (8 tablets) once. Simultaneous treatment of the sexual partner is not required.

With Amebiasis

In invasive forms of intestinal amoebiasis, adults and children over 10 years of age are prescribed 750 mg (3 tablets) 3 times a day. Children aged 3 to 7 years - 250 mg (1 tablet) 4 times a day; at the age of 7 to 10 years - 375 mg (1.5 tablets) 3 times a day. The course of treatment is usually 5 days. With amoebic liver abscess and other forms of extraintestinal amebiasis, adults and children over 10 years of age are prescribed 375 mg (1.5 tablets) 3 times a day. Children aged 3 to 7 years - 125 mg (1/2 tablet) 4 times a day; at the age of 7 to 10 years - 250 mg (1 tablet) 3 times a day. The course of treatment is 5 days.

With Giardiasis

Adults and children over 10 years of age are prescribed 500 mg (2 tablets) 2 times a day for 5-7 days; or 2000 mg (8 tablets) 1 time per day for 3 days. Children aged 3 to 7 years - 250-375 mg (1-1.5 tablets) 1 time per day for 5 days, or 500-750 mg (2-3 tablets) 1 time per day for 3 days. Children aged 7 to 10 years - 250 mg (1 tablet) 2 times a day for 5 days, or 1000 mg (4 tablets) 1 time per day for 3 days.

For infections caused by anaerobic bacteria

Adults - 400 mg 3 times a day for 7-10 days; children under 12 years old - 7.5 mg / kg 3 times a day.

With peptic ulcer of the stomach and duodenum

Assign 500 mg (2 tablets) 3 times a day for 7 days (as part of combination therapy).

Prevention of infections caused by anaerobic bacteria (before abdominal surgery, in gynecology and obstetrics)

Adults and children over 12 years of age are prescribed 250-500 mg (1-2 tablets) 3 times a day 3-4 days before surgery. 1-2 days after the operation, 250 mg (1 tablet) is prescribed 3 times a day for 7 days.

With chronic alcoholism

Inside, 500 mg (2 tablets) 1 time per day for 6 (no more) months.

For infections caused by anaerobic bacteria, adults and children over 12 years of age are prescribed the drug intravenously every 8 hours, 100 ml of a 0.5% solution (500 mg). Infusion is carried out at a rate of 5 ml/min. The maximum daily dose for intravenous administration is 4 g. The course of infusion therapy is 7-10 days, if necessary, 2-3 weeks. For children under 12 years of age, the dose for intravenous administration is set at the rate of 7.5 mg / kg of body weight (1.5 ml of a 0.5% metronidazole solution) every 8 hours. The drug is administered intravenously by drip, slowly. For the prevention of infections caused by anaerobic bacteria (before surgical operations on the abdominal cavity, in gynecology and obstetrics) For adults and children over 12 years old, the drug is administered at a dose of 500 mg (100 ml of a 0.5% solution) in/in drip slowly, the infusion is repeated after 8 hours Prophylactically, the drug is used no more than 12 hours after surgery.

For nonspecific vaginitis, 1 vaginal tablet is prescribed in combination with 2 tablets of Trichopolum for oral administration per day for 7 days or 1 vaginal tablet 2 times a day. The duration of treatment is no more than 10 days, courses of treatment should be carried out no more than 2-3 times a year. With trichomonas vaginitis, 1 vaginal tablet is prescribed per day for 10 days in combination with the intake of Trichopolum inside. The vaginal tablet should be removed from the contour pack, moistened with boiled chilled water and inserted deep into the vagina.

From the digestive system: pain in the stomach, nausea, vomiting, diarrhea, constipation, intestinal colic, decreased or no appetite, taste disturbance, unpleasant metallic taste in the mouth, dry mouth, glossitis, stomatitis; very rarely - abnormal liver function tests (ALT, AST, Bilirubin), jaundice, pancreatitis. From the nervous system: with prolonged use - headache, dizziness, impaired coordination of movements, ataxia, peripheral neuropathy, irritability, irritability, depression, sleep disturbance, drowsiness, weakness; in some cases - confusion, hallucinations, convulsions; very rarely - encephalopathy. From the urinary system: cystitis, polyuria, urinary incontinence, staining of urine in red-brown color. From the reproductive system: excessive development of the fungal flora of the vagina (including vaginal candidiasis), pain in the vagina. Allergic reactions: skin rash, itching, urticaria, nasal congestion, fever. From the musculoskeletal system: myalgia, arthralgia. From the hemopoietic system: leukopenia; rarely - agranulocytosis, neutropenia, thrombocytopenia. Other: extremely rare - toxic effect on the hearing aid; pustular eruptions.

Trichopol is categorically contraindicated in the following cases: hypersensitivity to metronidazole; blood diseases, leukopenia (including in the past); impaired coordination of movements, organic lesions of the nervous system (including epilepsy); severe liver and kidney failure; pregnancy (I trimester); lactation period.

Trichopol can not be taken in the first trimester of pregnancy. The use of the drug in the II and III trimesters is possible only in cases where the intended benefit to the mother outweighs the potential risk to the fetus. If it is necessary to use Trichopolum during lactation, breastfeeding should be stopped for a while.

Trichopol can cause serious side effects in patients with impaired liver, kidney, bone marrow, nervous system function, as well as in elderly patients. Violation of gait, dizziness and any other deterioration in the neurological status of patients requires discontinuation of treatment with Trichopolum. With prolonged therapy with metronidazole (more than 10 days), the picture of peripheral blood and liver function should be monitored. The possibility of developing dizziness should be taken into account when prescribing the drug to patients whose activities are related to the control of mechanisms, especially drivers of vehicles. Do not drink alcohol while taking Trichopolum.

The combined use of Trichopolum with some antibiotics (for example, erythromycin, gentamicin) enhances their antibacterial effect. At the same time, when taking certain sleeping pills (for example, phenobarbital), the effect of Trichopolum may decrease. Therefore, before you start using Trichopolum, tell your doctor about other medicines you are taking.

We have collected frequently asked questions and prepared answers to them.

Is there a difference in the dose in the treatment with Trichopolum regarding the disease (with giardiasis and with thrush, for example)?

Answer of the Medical Board

First of all, it should be clear that with thrush Trichopolum is not the first-line drug of choice and is used extremely rarely. This means that it does not have an antifungal effect, and its appointment with this diagnosis is justified only in the case of a chronic form, when thrush is accompanied by secondary infections.

With giardiasis, Trichopolum is allowed to be prescribed to children from the age of 3 according to the scheme:

3 - 7 years - within 5 days once at a dose of 250-375 mg. 7 - 10 years - course of treatment - 5 days, 2 tablets (250 mg) per day. Children after 10 years and adults - 6 days, 500 mg every 12 hours.

Regarding how to take Trichopol tablets before or after meals, and how many times a day to drink them - the drug is taken after or during meals, washed down with water, do not chew, in a dose according to age and doctor's prescription. How many days to take - also depends on the primary diagnosis, for example, with alcoholism it is allowed to drink up to 6 months, with giardiasis - no longer than 7 days. Some sources also indicate that Trichopolum helps with acne (Trichopolum tablet should be crushed into powder, mixed with water and applied to the problem area of ​​the face).

How correctly, in what dose and from what age is Trichopolum allowed to be given to children?

Answer of the Medical Board

First, it is worthwhile to understand that children under one year old cannot be used. Its use is allowed only after 3 years of age. Usually Trichopolum is assigned to children from lamblia. Depending on the diagnosis, the dosage is 1-2 tablets 3-4 times a day.

In exceptional cases, it can be used in children under 3 years of age with diarrhea that lasts more than 10 days. A single dose in this case should be calculated as follows: 5 mg of Trichopolum per 1 kg of body weight of the child, taking a dose every 8 hours for 48 hours.

Is it really forbidden to take Trichopolum during early pregnancy and during breastfeeding?

Answer of the Medical Board

During pregnancy, Trichopol is categorically contraindicated, especially in the first 12 weeks of pregnancy. It is allowed to prescribe it to pregnant women only if the benefit to the mother outweighs the risk to the fetus.

During lactation, its use is also contraindicated, since the drug passes into breast milk. For the duration of treatment, it is worth stopping breastfeeding, it can be resumed 2 days after the last tablet of Trichopolum.

How to drink Trichopolum correctly and in what dose for a man in case of diagnosed trichomoniasis?

Answer of the Medical Board

In the case of diseases that are sexually transmitted, it is important that both partners undergo treatment with Trichopolum at the same time, which also applies to trichomoniasis. A man should take 1 tab. per day for 10 days. A woman is prescribed the same course, but 2 tab. per day, and additionally for a vaginal suppository 1 time in 24 hours.

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With the development of viruses and bacteria that cause itching in the vagina, doctors may prescribe Trichopolum - the instructions for use of the drug contain information about the indications for its use and the correct dosage. The drug belongs to antibacterial, used in gynecology. Familiarize yourself with its dosage, side effects and drug interactions described in the instructions for use.

According to the pharmaceutical classification, Trichopolum belongs to antiprotozoal drugs with antibacterial activity. The agent is intended for topical application in gynecology, infusion therapy and oral administration in the complex treatment of diseases. This medicine is produced in several formats, the active substance in each is metronidazole.

Trichopol has three release formats: oral and vaginal tablets (erroneously called suppositories) and a solution for infusion. Detailed composition of each medicine:

	vaginal tablets		oral tablets
Metronidazole concentration, mg	500 for 1 piece	5 per 1 ml / 100 or 500 per 1 ampoule	250 for 1 tablet
Additional substances	Povidone, stearic acid, microcrystalline cellulose, colloidal silicon dioxide, crospovidone	Monohydrate citric acid, water, sodium chloride and hydrogen phosphate	Magnesium stearate, gelatin, molasses, corn starch
Description	White with a yellow tint, oblong, biconvex	Transparent, yellow with a green tint	White, round
Package		20 ampoules from clear glass in a pack / 100 ml in a polyethylene bottle

The active substance of the drug belongs to nitroimidazoles. The mechanism of its action includes the biochemical reduction of the nitro group by intracellular proteins of anaerobic microorganisms and protozoa. When metronidazole interacts with cell DNA, the production of nucleic amino acids is suppressed, which leads to the death of the microorganism that causes the disease. The substance has antimicrobial properties.

When administered intravaginally, it is well absorbed, biotransformation occurs in the liver, excreted by the kidneys. After oral administration, it is absorbed from the stomach, with intravenous drip it is distributed through tissues and biological fluids. It binds to plasma proteins by 20%. In the liver, up to 60% of metronidazole is metabolized, the half-life is 8 hours, it is excreted in the urine and feces.

According to the instructions, the use of Trichopolum is actively practiced for local treatment in gynecology. Vaginal tablets eliminate the source of the disease in the genitals, oral tablets do not allow the pathogen to develop in the intestines, and the solution - in the blood. Depending on the release format, the indications for the use of the drug Trichopol differ slightly.

The oral form of release of the antifungal drug Trichopolum is effective in protozoal and genital infections of the genitourinary tract:

• trichomoniasis therapy;
• treatment of giardiasis, amoebiasis;
• balantidia, leishmaniasis;
• trichomonas urethritis in men and vaginitis in women;
• bacterial infections of the joints, heart;
• bacterial endocarditis, pulmonary pneumonia;
• ovarian abscess, endometritis;
• stomach ulcer;
• helicobacter infection;
• cystitis (complex therapy).

Erroneously referred to as vaginal suppositories, vaginal tablets, according to the instructions for use, have the following indications, in which they are prescribed by doctors for the local treatment of gynecological problems:

• nonspecific vaginitis;
• bacterial vaginosis;
• trichomonas vaginitis;
• as part of complex treatment with Nystatin, a chronic form of thrush is treated.

According to the instructions for use, the solution for infusion injection Trichopolum is used for the following indications:

• chronic complicated trichomoniasis;
• giardiasis;
• peritonitis, abscess of the abdominal cavity and liver, ovaries and fallopian tubes, lung, brain;
• endometritis;
• complications after surgery;
• pneumonia, pleural empyema;
• meningitis;
• skin infections;
• prevention of complications during operations on the colon, removal of the appendix;
• in combination with bismuth and amoxicillin for peptic ulcer disease.

The drug in the form of a solution and oral tablets is used parenterally and orally. The dosage depends on the severity of the disease and the age of the patient:

1. Trichomoniasis in adults - 250 mg tablets after meals for 10 days. Analyzes are done at intervals of 3-4 weeks.
2. Amebiasis adults - 250 mg three times / day, 5-10 days. The dose for children is calculated as 35-50 mg / kg body weight / day, divided into three doses. The course will be 10 days.
3. With symptoms of giardiasis - 500 mg / day for children over 10 years old, 6-10 years old, 375 mg / day, 2-5 years old - 250. The daily dose is divided into two doses, taken for 5-10 days. The course is repeated in 1-1.5 months.
4. Helps Trichopol from the throat with sore throat - a tablet dissolved in water, you need to rinse your mouth.
5. From acne - drink a course of tablets or lubricate the affected areas with a solution.
6. Infectious diseases caused by anaerobic bacteria in children over 12 years of age - intravenously injected 0.5% solution every 8 hours, 100 ml. The maximum daily dose is 4 g, the course lasts up to 10 days, maximum - 21 days. Up to 12 years of age, the dose is considered as 7.5 mg / kg every 8 hours.
7. For the prevention of surgical infections before the intervention, an infusion solution is administered 5-10 minutes before the operation. At the age of over 12 years - 500 mg intravenously in drops slowly, repeated after 8 hours, but not more than 12 hours. Up to 12 years - 7.5 mg / kg.
8. Tablets for the prevention of infections are taken orally - over 12 years old, a single dose will be 1 g (4 pcs.), Then 250 mg three times / day. Children 5-12 years old - 125 mg every 8 hours for a total of 48 hours. Newborns and toddlers up to 5 years - 5 mg / kg every 8 hours.
9. Peptic ulcer - a daily dose of 0.5 g in two divided doses.
10. Bacterial vaginitis - 1 g / day, if the disease is caused by anaerobic infections - 1.5 g. In case of impaired renal function, the dosage is reduced three times.

For intravaginal use, Trichopol vaginal tablets are intended. According to the instructions, they are prescribed in the following dosage depending on the disease:

• trichomonas vaginitis - 1 piece / day for 7-10 days with oral tablets;
• nonspecific vaginitis, bacterial vaginosis - 1 pc. per day for 7 days;
• treatment can not be longer than 10 days, used more often 2-3 times a year;
• the tablet is removed from the package, moistened with boiled cool water, inserted deep into the vagina.

Instructions for use medicinal product contains a special instructions section that provides important information to the patient:

• at the same time, the sexual partner is treated, even if he does not have manifestations of diseases of the reproductive flora;
• during the period of treatment it is recommended not to have sexual intercourse;
• when changing the composition of the blood or after taking the drug in high doses, medical supervision is necessary;
• causes dizziness when taken orally, so you should refrain from driving and dangerous machinery;
• patients with impaired liver function undergo dosage adjustment;
• with caution is prescribed with a tendency to the appearance of edema, infectious therapy with glucocorticosteroids;
• urine may turn darker in color;
• it is possible to obtain false readings in the analysis of blood plasma;
• the instructions do not say about the safety of the product in relation to children under 5 years old.

The active substance of the drug passes through the placenta and can damage the fetus, so it is forbidden to prescribe Trichopolum in the first trimester of pregnancy. In the second and third trimesters, the intake is carried out according to the instructions, if the doctor has established an excess of benefit for the mother over the risk to the child. The components of the drug are excreted in breast milk, so it is better to cancel breastfeeding when using Trichopolum and resume two days after the end of its administration.

Instructions for use Trichopol indicates its possible interaction with other drugs:

• compatible with antibiotics, sulfonamides;
• causes intolerance to ethanol, it is forbidden to drink alcohol during treatment;
• disulfiram depresses consciousness, develops mental disorders;
• do not combine metronidazole with muscle relaxants;
• barbiturates accelerate the metabolism of the concentration of the drug in the liver, which reduces its effectiveness;
• cimetidine inhibits the action of metronidazole, which leads to an increase in its concentration and the development of side effects;
• lithium preparations increase the concentration of lithium in the blood, increase the toxicity of the metal;
• asetmizole and terfenadine lead to arrhythmia, heart block, fainting;
• reduces the clearance of phenytoin.

The instructions for use of the drug indicate possible side effects during its use:

• itching, burning, pain, irritation of the vaginal mucosa;
• thick white discharge;
• frequent urination;
• the occurrence of candidiasis after the drug;
• loss of taste, loss of appetite;
• headaches, dizziness;
• allergies, hives, rash or itching on the skin;
• burning or irritation of the partner's penis;
• sleep disturbances, depression, seizures, hearing problems;
• thrombophlebitis with intravenous administration.

There are no data on overdose with vaginal tablets. Symptoms of an overdose of oral tablets and Trichopol solution are convulsions, peripheral neuropathy, neurological symptoms. When taking more than 15 g of the drug at a time, nausea, vomiting were observed, the patient lost coordination of movements. Treatment methods for drug overdose include symptomatic therapy.

Instructions for use Trichopol indicates the following contraindications, in which the drug is prohibited:

• leukopenia;
• lack of coordination;
• organic lesions of the central nervous system, epilepsy;
• liver failure;
• first trimester of pregnancy, lactation;
• hypersensitivity to the constituent substances, derivatives of nitroimidazole.

In pharmacies, Trichopol preparations can only be bought with a prescription. They are stored in a dry, dark place without the access of children at temperatures up to 25 degrees. Shelf life is three years for tablets and five years for solution.

According to the active active ingredient and the pharmacological effect on the body, the following analogues of the drug are distinguished in the form of tablets, suppositories and solutions, produced in the Russian Federation and abroad:

• Metronidazole;
• Klion;
• Metrogyl;
• Metron;
• Bacimex;
• Gravagin;
• Mistol;
• Flagyl;
• Gynomax;
• Ginalgin;
• Ginezol;
• Myco-Penotran;
• Guino-Pevaril;
• Santequin.

You can buy medicine through online pharmacies or the usual pharmaceutical departments. The cost will depend on the form of release and the manufacturer. Approximate prices:

Valeria, 45 years old

Last year, I noticed that I started having thick, profuse vaginal discharge that smelled like fish. The gynecologist diagnosed bacterial vaginosis and prescribed Trichopol vaginal tablets. I used them according to the instructions and reviews - moistened with water and inserted as deep as possible. Within a week the symptoms were gone.

Alexander, 30 years old

In winter, I caught a bad cold, did not treat my cold in time and fell ill with a sore throat. Doctors prescribed a bunch of antibiotics and advised to gargle with a disinfectant that kills streptococci. The choice fell on Trichopol tablets. I read the reviews on them and was pleasantly surprised by the result after the treatment. The pus went away faster, there were no side effects.

Alina, 29 years old

I have a chronic form of thrush, so I constantly maintain a state in which relapses would not occur. If they have occurred, the proven scheme of Nystatin and Trichopolum helps. I take both drugs in a complex, and the thrush passes faster. Separately, they do not work, so it turns out only together.

It is also effective against anaerobic microorganisms and some gram-positive pathogens. Against a fungal infection, this drug is powerless, but can be prescribed by a doctor in complex therapy.

The tablets contain active substance metronidazole (500mg). Additional components:

• stearic acid;
• gelatin;
• povidone;
• starch syrup;
• potato starch;
• microcrystalline cellulose.

Trichopol vaginal tablets (500 mg) have White color with a yellow coating, elongated shape, biconvex.

Composition of vaginal tablets:

• metronidazole
• microcrystalline cellulose;
• crospovidone;
• povidone;
• stearic acid.

All these components provide the proper therapeutic effect: the DNA of the bacterium is disrupted, which leads to its death, and as a result, the person recovers.

Trichopol begins to act within 3 hours after administration.

Tablets and suppositories Trichopol: what is suitable for the treatment of gynecological diseases

Trichopolum has several forms of release:

1. Gynecological suppositories or tablets. This is a special form of a medicinal substance that treats various infectious diseases MPS.
2. Tablets for oral administration.
3. Solution for douching or for intravenous administration.

Gynecologists in the treatment of female ailments prefer to use suppositories or vaginal tablets that act locally without irritating the gastrointestinal tract. Candles come in three main shapes:

• ovoid;
• flat;
• spherical.

Benefits of candles:

1. Rapid absorption into the blood.
2. Does not lose its properties during absorption.
3. Candles leave no trace on internal organs: liver and kidneys.
4. Does not weaken the immune system.
5. Hypoallergenic.
6. They act locally.
7. Simplicity and ease of use.
8. Reliably fixed on the mucosa, have a therapeutic effect on the focus of the disease.

What gynecological diseases does Trichopolum treat?

Indications for the use of Trichopolum in gynecology:

• trichomoniasis;
• endometritis;
• vaginitis;
• chlamydia;
• gonorrhea.

Treatment with Trichopolum for thrush

Thrush is one of the most common diseases in gynecology, caused by a type of Candida fungus. The instructions with indications for the use of Trichopolum indicate that the drug is strong only against gonococci, Trichomonas, cocci.

Therefore, although it is believed that candidiasis can be cured with this medication, Trichopolum will not help, as it is not sensitive to the Candida fungus. It can only act as an additional therapy for other concomitant diseases.

• Pimmafucin;
• Fluconazole;
• Flucostat.

Trichopol in the treatment of trichomoniasis

In gynecology, Trichomonas vaginalis is quite common - trichomoniasis that affects the lower part of the human MPS. The disease is inherent in sexually active men and women in the age range from 20 to 40 years.

To combat this disease in gynecology, Trichopol is usually prescribed. According to the indications for use, trichomoniasis is sensitive to the components of this medication.

The drug is taken in a course for 10 days, 250 mg per day. Since the disease is sexually transmitted, both partners are treated simultaneously.

During the period of therapy, intimate contacts, as well as alcohol and spicy foods, are excluded. To avoid the consequences and negative manifestations after taking Trichopolum, according to the indications for use in gynecology, you need to add fermented milk products to your menu: yogurt, kefir, fermented baked milk.

At the end of therapy, it is necessary to repeat the tests to exclude the occurrence of relapse within 3 menstrual cycles.

Treatment with Trichopolum for bacterial vaginosis

Antibiotics adversely affect the state of the immune system and the microclimate female body. Long-term use of such medications contributes to the development of bacterial flora.

This process is called bacterial vaginosis. The causative agent of vaginosis are bacteria of the gardnerella species, which are very susceptible to the drug Trichopolum.

Signs of the disease: profuse and frequent discharge, painted in a gray-green color.

Treatment with Trichopolum:

The dosage of the drug is calculated by the doctor, taking into account the age of the patient. The usual dosage is 1g/day. The recommended course is from 5 to 10 days.

Treatment of infections caused by anaerobic bacteria

Anaerobic bacteria cause inflammatory processes in the body in the following organs:

• urinary tract;
• in the appendages of the uterus;
• in the area of ​​the vagina.

Therapy with Trichopolum consists in taking 2 tablets 3-4 times a day at a dosage of 500 mg. The course of treatment is 1 week.

Can Trichopol be used during pregnancy and lactation

Trichopolum during the period of expectation of a child should be used very carefully, especially in the 1-3 trimester. Gynecologists consider this period to be a contraindication, since the medication can adversely affect the development of the fetus.

Trichopol is prescribed only if the risk to the health of the expectant mother is higher than the risk to the child.

Indications for the use of Trichopolum in gynecology during pregnancy are prescribed by a doctor

Special instructions for the use of Trichopolum

When using the medication, you need to know the following:

1. Metronidazole contains water-soluble dyes, so the urine may have a dark color.
2. If the patient has excessive swelling, Trichopolum is prescribed extremely rarely.
3. Minor patients are not recommended to take Trichopol together with Amoxicillin. It is necessary to periodically donate blood for analysis.
4. It is necessary to avoid, if possible, activities that require special attention and quick response (for example, this applies to driving a car).

Who should not take Trichopolum: contraindications

• liver failure;
• individual intolerance;
• pregnancy, especially in the first trimester;
• epilepsy and disorders of the central nervous system;
• leukopenia;
• kidney failure.

Side effects when taking Trichopolum in gynecology

Side effects can be observed from various body systems.

From the gastrointestinal tract:

• epigastric pain;
• loss of appetite;
• dyspeptic phenomena;
• colitis;
• intestinal disorders;
• allergies to the drug;
• constipation.

Diseases of the oral cavity:

• stomatitis;
• signs of taste disturbance.

From the side of the central nervous system:

• headache;
• improper coordination of movements;
• excitability and irritability;
• signs of insomnia;
• frequent ailments;
• fatigue.

In exceptional cases, patients experience hallucinations, delusions and convulsions.

From the MPS:

• dysuria;
• cystitis;
• enuresis.

Skin diseases:

• allergy;
• skin rashes;
• intolerable itching;
• urticaria syndrome.

Muscular system:

• acute muscle pain;
• acute pain in the joints.

Hematopoiesis: leukopenia.

How much does Trichopol cost in a pharmacy

The average check for the drug Trichopolum is 220-300 rubles. Vaginal suppositories - 190-275 rubles. for 10 pieces.

Trichopol, indications for use in gynecology discussed above, is an inexpensive and effective drug in the treatment of various inflammatory processes. Correct Application Trichopolum, taking into account contraindications and observing a number of precautions, can avoid undesirable consequences.

Video clips about Trichopolum

Trichopol instruction. Indications for use in gynecology:

Trichopol analogue:

The drug Trichopolum is most often used for trichomoniasis. The causative agents of the disease are highly sensitive to this remedy. Therefore, it has been successfully used to treat both acute and chronic trichomoniasis, which can be complicated by other infections. Trichomoniasis, treatment with Trichopolum which is quite effective, in no case should you try to overcome it yourself. If this disease is detected, a doctor should prescribe a course of treatment.

Trichomoniasis is usually treated with both topical and systemic drugs. Local medication eliminates discomfort and pain in the genitals, and the general one fights pathogens inside the body. It is necessary to take this antibiotic in a course. It usually lasts ten days. Adult patients are prescribed 250 mg twice a day. If the disease is started, the treatment is prolonged.

During therapy, it is important to limit yourself in the choice of dishes, excluding everything spicy, salty and fried. Alcoholic drinks are completely contraindicated. They can not be used even within a day after taking the drug. Sexual contact at this time is also excluded. To reduce side effects from the use of Trichopolum from trichomoniasis, fermented milk products should be included in the diet, especially those that contain bifidobacteria - yogurt, kefir and others. This is necessary in order to prevent dysbacteriosis, which provokes an antibiotic.

Patients with trichomoniasis should also take drugs that strengthen the immune system. After a course of treatment with both Trichopolum and other means, tests should be taken. This should be done one week after you stop taking this drug. Then the tests are given every month. The patient is considered healthy if examinations show no infection.

Before taking Trichopolum for trichomoniasis, each patient should be aware of the possible side effects. For example, but can cause stomatitis or dry mouth. Rarely, trichopolum provokes the development of hepatitis or pancreatitis. From the side of the nervous system, headache and blurred vision, as well as ataxia and other diseases, are possible. Anemia is also excluded. allergic reaction and other side effects.

To reduce the risk of various side effects, you need to consult with your doctor about which supplements you can use for prevention. Also, the specialist should find out if the patient has any contraindications to the use of this drug.